1: Pseudomonas capacia / Microbiological reaction 2: PPh3; H2O / tetrahydrofuran / 55 °C 3: Et3N / 20 °C 4: 88 percent / imidazole / 20 °C 5: 92 percent / NaH / dimethylformamide / 20 °C 6: 95 percent / Grubb's catalyst / CH2Cl2 / Heating 7: 96 percent / nBu4NF / tetrahydrofuran / 20 °C 8: 72 percent / m-chloroperbenzoic acid / CH2Cl2 / Heating 9: KOH (1 percent) / Heating View Scheme