(R)-(+)-1-(2-萘基)乙醇合成路线 （共 65 条）
反应条件
α-naphthol; C136H102Fe2N4O6 in toluene T=50°C; 18 h; optical yield given as percent ee;
参考文献
Kunisu, Takashi; Oguma, Takuya; Katsuki, Tsutomu
Journal of the American Chemical Society, 2011 , vol. 133, # 33 p. 12937 - 12939
反应条件
hydrogenchloride T=20°C; 0.5 h;
参考文献
Duan, Wei-Liang; Shi, Min; Rong, Guo-Bin
Chemical Communications, 2003 , # 23 p. 2916 - 2917
反应条件
1,3-di[(R)-(+)-α-methylbenzyl]imidazolium tetrafluoroborate; potassium tert-butylate in tetrahydrofuran T=-78°C; 1.5 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Kano, Taichi; Sasaki, Kouji; Maruoka, Keiji
Organic Letters, 2005 , vol. 7, # 7 p. 1347 - 1349
反应条件
phosphate buffer; lipase T=20°C;
参考文献
Laumen, Kurt; Schneider, Manfred P.
Journal of the Chemical Society, Chemical Communications, 1988 , p. 598 - 600
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=20°C; Inert atmosphereAnhydrous conditions; enantioselective reaction;
参考文献
Leclercq, Loic; Suisse, Isabelle; Agbossou-Niedercorn, Francine
European Journal of Organic Chemistry, 2010 , # 14 p. 2696 - 2700
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=20°C; Inert atmosphereAnhydrous conditions; enantioselective reaction;
参考文献
Leclercq, Loic; Suisse, Isabelle; Agbossou-Niedercorn, Francine
European Journal of Organic Chemistry, 2010 , # 14 p. 2696 - 2700
反应条件
1: methyllithium in diethyl ether; toluene T=-5°C; 1 h; Inert atmosphere; 2: With titanium(IV) isopropylate in diethyl ether; toluene T=-5°C; Inert atmosphere; 3: β-naphthaldehyde in diethyl ether; toluene T=-5°C; 24 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Huang, Changwei; Yang, Nianfa; Zhang, Anlin; Yang, Liwen
Polymer (United Kingdom), 2012 , vol. 53, # 16 p. 3514 - 3519
反应条件
Candida antarctica B lipase; butan-1-ol in acetonitrile 168 h;
参考文献
Swaleh, Sauda M; Hungerhoff, Benno; Sonnenschein, Helmut; Theil, Fritz
Tetrahedron, 2002 , vol. 58, # 20 p. 4085 - 4089
反应条件
(R)-7-chloro-2-phenyl-2,3-dihydroimidazo[1,2-a]quinoline; N-ethyl-N,N-diisopropylamine in chloroform T=0°C; 8 h; Product distribution; Further Variations:Reagents;
参考文献
Birman, Vladimir B.; Li, Ximin
Organic Letters, 2006 , vol. 8, # 7 p. 1351 - 1354
反应条件
1: 90 percent / diethyl ether / 2.5 h / 0 - 20 °C 2: IL1 / lipase PS-C / diisopropyl ether / 21.5 h / 35 °C View Scheme
参考文献
Itoh, Toshiyuki; Matsushita, Yuichi; Abe, Yoshikazu; Han, Shi-Hui; Wada, Shohei; Hayase, Shuichi; Kawatsura, Motoi; Takai, Shigeomi; Morimoto, Minoru; Hirose, Yoshihiko
Chemistry - A European Journal, 2006 , vol. 12, # 36 p. 9228 - 9237
