1-(1-甲基-2-苯基 乙烯)-吡咯烷合成路线 （共 13 条）
反应条件
1: in benzene T=5 - 35°C; 1 h; 2: With hydrogenchloride in water T=25 - 35°C; 5 h; Heating / reflux; Product distribution / selectivity;
参考文献
Dr. Reddy's Laboratories Ltd.; Dr. Reddy's Laboratories, Inc.
Patent: EP1550658 A1, 2005 ;
Location in patent: Page/Page column 8-9 ;
反应条件
1: With triethylamine in dichloromethane T=25 - 35°C; 3 h; 2: With hydrogenchloride in water T=100°C; 3 h;
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
反应条件
1: triethylamine / dichloromethane / 5 - 35 °C / Large scale reaction 2: hydrogenchloride / water / 98 - 102 °C / Large scale reaction View Scheme
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
反应条件
1: With triethylamine in dichloromethane T=25 - 35°C; 3 h; 2: With hydrogenchloride in water T=100°C; 3 h;
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
反应条件
1: triethylamine / dichloromethane / 5 - 35 °C / Large scale reaction 2: hydrogenchloride / water / 98 - 102 °C / Large scale reaction 3: chlorosulfonic acid / dichloromethane / 0 °C / Reflux 4: water / tetrahydrofuran / 24 h / Reflux View Scheme
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
反应条件
1.1: triethylamine / dichloromethane / 5 - 35 °C / Large scale reaction 2.1: hydrogenchloride / water / 98 - 102 °C / Large scale reaction 3.1: chlorosulfonic acid / dichloromethane / 0 °C / Reflux 3.2: 1 h / 25 - 35 °C View Scheme
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
反应条件
(i) iPr2NEt, pentane, (irradiation), (ii) aq. H2SO4; Multistep reaction;
参考文献
Cantacuzene,D. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 1365 - 1371
反应条件
1: triethylamine / dichloromethane / 5 - 35 °C / Large scale reaction
2: hydrogenchloride / water / 98 - 102 °C / Large scale reaction
3: chlorosulfonic acid / dichloromethane / 0 °C / Reflux
View Scheme
参考文献
Reddy, Anumula Raghupathi; Goverdhan, Gilla; Sampath, Aalla; Mukkanti, Khagga; Reddy, Padi Pratap; Bandichhor, Rakeshwar
Synthetic Communications, 2012 , vol. 42, # 5 p. 639 - 649
反应条件
potassium carbonate in diethyl ether
72 - 96 h; Product distribution / selectivity;
参考文献
Dr. Reddy's Laboratories Ltd.; Dr. Reddy's Laboratories, Inc.
Patent: EP1550658 A1, 2005 ;
Location in patent: Page/Page column 8 ;
反应条件
[(1,2-bis(diisopropylphosphino)ethane)NiCl2]
T=180°C; 72 h; Schlenk techniqueInert atmosphere;
参考文献
Reyes-Sanchez, Adan; Garcia-Ventura, Ilnett; Garcia, Juventino J.
Dalton Transactions, 2014 , vol. 43, # 4 p. 1762 - 1768
