1: With hydrogen; Rh/Al2O3 in tetrahydrofuran P=2585.81 Torr; 6 h; 2: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 14 h; 3: With water in tetrahydrofuran; diethyl ether
参考文献
Allergan, Inc.
Patent: US2008/255239 A1, 2008 ;
Location in patent: Page/Page column 38 ;
US 20080255239 A1
1: With lithium triethylborohydride in tetrahydrofuran T=-78 - 20°C; 19 h; 2: With water in tetrahydrofuran 2 h; Heating; 3: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran T=20°C; 1 h;
