1-苯基-3,4-二氢异喹啉合成路线 （共 40 条）
反应条件
alpha-chloropyridine; trifluoromethylsulfonic anhydride in dichloromethane T=-78 - 45°C; Bischler-Napieralski reaction; Inert atmosphere;
参考文献
Movassaghi, Mohammad; Hill, Matthew D.
Organic Letters, 2008 , vol. 10, # 16 p. 3485 - 3488
反应条件
sulfur in pyridine 1.) 3 h, 100 deg C, 2.) 12 h, r.t.;
参考文献
Ajzert, Ilona K.; Takacs, Kalman
Liebigs Annalen der Chemie, 1987 , p. 1061 - 1064
反应条件
hydrogenchloride; borane-ammonia complex in aq. phosphate buffer T=37°C; pH=7.8;
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
1: 83.3 percent / Et3N / CH2Cl2 / 4 h / 20 °C 2: 82.4 percent / P2O5; POCl3 / xylene / 3 h / Heating View Scheme
参考文献
Yang, Jie; Hua, Wei-Yi; Wang, Fu-Xiang; Wang, Zhi-Yuan; Wang, Xiang
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 24 p. 6547 - 6557
反应条件
sodium hydroxide; sodium hydrogen telluride in ethanol 18 h; Heatingat pH 10-11;
参考文献
Barton, Derek H.R.; Fekih, Abdelwaheb; Lusinchi, Xavier
Tetrahedron Letters, 1985 , vol. 26, # 38 p. 4603 - 4606
反应条件
tin(IV) chloride in chloroform 100 h;
参考文献
Nagubandi, Sreeramulu; Fodor, G.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1457 - 1463
反应条件
trichlorophosphate in 1,2-dichloro-benzene T=140 - 150°C; 0.05 h; Irradiation; Yields of byproduct given;
参考文献
Bose, Ajay K.; Manhas, Maghar S.; Ghosh, Malay; Shah, Mamta; Raju, Vegesna S.; et al.
Journal of Organic Chemistry, 1991 , vol. 56, # 25 p. 6968 - 6970
反应条件
1: trichloroisocyanuric acid / dichloromethane / 1.5 h / 3 - 5 °C 2: potassium hydroxide / methanol / 1 h / 20 °C View Scheme
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
1: 92 percent / 10percent aq. NaOH / CH2Cl2 / 0.25 h 2: 1 g / POCl3, P2O5 / 2 h / Heating View Scheme
参考文献
Yang, Jie; Hua, Wei-Yi; Wang, Fu-Xiang; Wang, Zhi-Yuan; Wang, Xiang
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 24 p. 6547 - 6557
反应条件
potassium hydroxide in methanol T=20°C; 1 h;
参考文献
Bolchi, Cristiano; Pallavicini, Marco; Fumagalli, Laura; Straniero, Valentina; Valoti, Ermanno
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 432 - 437
