1-苯基-3,4-二氢异喹啉盐酸盐合成路线 （共 7 条）
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; (S)-P-Phos; phosphoric acid in tetrahydrofuran T=65°C; P=22502.3 Torr; 20 h; optical yield given as percent ee;
参考文献
Ruzic, Milos; Pecavar, Anica; Prudic, Darja; Kralj, David; Scriban, Corina; Zanotti-Gerosa, Antonio
Organic Process Research and Development, 2012 , vol. 16, # 7 p. 1293 - 1300
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; (S)-P-Phos; phosphoric acid in tetrahydrofuran T=60°C; P=22502.3 Torr; 72 h; optical yield given as percent ee;
参考文献
Organic Process Research and Development, , vol. 16, # 7 p. 1293 - 1300
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; (S)-P-Phos; phosphoric acid in tetrahydrofuran T=65°C; P=22502.3 Torr; 20 h; optical yield given as percent ee;
参考文献
Organic Process Research and Development, , vol. 16, # 7 p. 1293 - 1300
反应条件
sodium tetrahydroborate in methanol T=20°C; 3 h;
参考文献
Bolchi, Cristiano; Pallavicini, Marco; Fumagalli, Laura; Straniero, Valentina; Valoti, Ermanno
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 432 - 437
反应条件
1: With phosphorous pentoxide; trichlorophosphate in anhydrous xylene
T=140°C; 5 h;
2: With hydrogenchloride in tert-butyl methyl ether; water
1 h;
参考文献
Ruzic, Milos; Pecavar, Anica; Prudic, Darja; Kralj, David; Scriban, Corina; Zanotti-Gerosa, Antonio
Organic Process Research and Development, 2012 , vol. 16, # 7 p. 1293 - 1300
反应条件
in dichloromethane
T=20°C;
参考文献
Bolchi, Cristiano; Pallavicini, Marco; Fumagalli, Laura; Straniero, Valentina; Valoti, Ermanno
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 432 - 437
反应条件
1.1: dichloromethane / 2 h / 0 - 5 °C
1.2: 6 h / 0 °C / Reflux
2.1: phosphorous pentoxide; trichlorophosphate / anhydrous xylene / 5 h / 140 °C
2.2: 1 h
View Scheme
参考文献
Ruzic, Milos; Pecavar, Anica; Prudic, Darja; Kralj, David; Scriban, Corina; Zanotti-Gerosa, Antonio
Organic Process Research and Development, 2012 , vol. 16, # 7 p. 1293 - 1300
