5-甲氧基-2-乙烯基苯酚合成路线 （共 5 条）
反应条件
1: 48 percent / K2CO3 / dimethylformamide 2: 78 percent / Grubbs second-generation catalyst / CH2Cl2 / 20 °C View Scheme
参考文献
Polito, Laura; Cravini, Massimiliano; Poletti, Laura; Lay, Luigi
Synthetic Communications, 2006 , vol. 36, # 15 p. 2203 - 2209
反应条件
potassium tert-butylate in tetrahydrofuran
T=30°C; Wittig Olefination; Inert atmosphere;
参考文献
Seoane, Andres; Casanova, Noelia; Quinones, Noelia; Mascarenas, Jose L.; Gulias, Moises
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 834 - 837
反应条件
1: triphenyl-methyl-phosphonium iodide With n-butyllithium in tetrahydrofuran; hexane
T=0°C; 2 h;
2: 2-Hydroxy-4-methoxy-benzaldehyde in tetrahydrofuran; hexane
T=-78°C; Wittig reaction;
参考文献
Polito, Laura; Cravini, Massimiliano; Poletti, Laura; Lay, Luigi
Synthetic Communications, 2006 , vol. 36, # 15 p. 2203 - 2209
反应条件
1.1: 65 percent / K2CO3 / acetonitrile / 1 h / Heating
2.1: BuLi / hexane; tetrahydrofuran / 2 h / 0 °C
2.2: 99 percent / hexane; tetrahydrofuran / -78 °C
View Scheme
参考文献
Polito, Laura; Cravini, Massimiliano; Poletti, Laura; Lay, Luigi
Synthetic Communications, 2006 , vol. 36, # 15 p. 2203 - 2209
反应条件
tributyl-amine; tin(IV) chloride; potassium carbonate
1) C6H5Cl, 2) C6H5Cl, 60 deg C, 30 min, 3) MeOH, reflux, 30 min; Multistep reaction;
参考文献
Yamaguchi, Masahiko; Arisawa, Mieko; Omata, Kenji; Kabuto, Kuninobu; Hirama, Masahiro; Uchimaru, Tadafumi
Journal of Organic Chemistry, 1998 , vol. 63, # 21 p. 7298 - 7305
