2,2-二甲基-1,4-二氢-2H-苯并[d][1,3]噁嗪合成路线 （共 6 条）
反应条件
acetic acid in water T=0 - 20°C; 6.5 h;
参考文献
Theravance, Inc.
Patent: US2006/199839 A1, 2006 ;
Location in patent: Page/Page column 24 ;
US 20060199839 A1
反应条件
toluene-4-sulfonic acid in benzene HeatingContinuous removal of water;
参考文献
Mao, Yuh-lin; Boekelheide, V.
Journal of Organic Chemistry, 1980 , vol. 45, # 8 p. 1547 - 1548
反应条件
1: 76 percent / Amberlist 15 / CHCl3 / 24 h / Heating 2: 1.) TEACl, 2.) proton / 1.) acetonitrile, -10 deg C, electrochemical reaction View Scheme
参考文献
Tilborg, W. J. M. van; Plomp, R.; Ruiter, R. de; Smit, C. J.
Recueil: Journal of the Royal Netherlands Chemical Society, 1980 , vol. 99, # 6 p. 206 - 212
反应条件
sodium tetrahydroborate in ethanol; toluene
参考文献
Yamakawa; Matsukura; Nomura; Yoshioka; Masaki; Igata; Okabe
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 7 p. 1746 - 1752
反应条件
T=750°C; P=0.01 Torr;
参考文献
Journal of Organic Chemistry, , vol. 45, # 8 p. 1547 - 1548
反应条件
1.) pyrolysis; 2.) -78 deg C; Yield given. Multistep reaction;
参考文献
Barker, S. J.; Jones, G. B.; Randles, K. R.; Storr, R. C.
Tetrahedron Letters, 1988 , vol. 29, # 8 p. 953 - 954
