3-苄基-3-杂氮双环[3.2.1]-8-辛醇合成路线 （共 5 条）
反应条件
tris(triphenylphosphine)ruthenium(II) chloride; potassium tert-butylate in toluene
7 h; Reflux;
参考文献
Nippon Soda Co., Ltd.
Patent: EP2080755 A1, 2009 ;
Location in patent: Page/Page column 6 ;
反应条件
aluminum isopropoxide; cyclohexanol in toluene
17 h; Reflux;
参考文献
Nippon Soda Co., Ltd.
Patent: EP2184274 A1, 2010 ;
Location in patent: Page/Page column 7 ;
反应条件
1: With aluminum isopropoxide in toluene
0.5 h; Inert atmosphereReflux;
2: With cyclohexanone in toluene
13 h; Reflux;
参考文献
Nippon Soda Co., Ltd.
Patent: EP2184274 A1, 2010 ;
Location in patent: Page/Page column 7 ;
反应条件
1: With aluminum isopropoxide in toluene
2.5 h; RefluxInert atmosphere;
2: With cyclohexanone in toluene
7 h; Reflux; Product distribution / selectivity;
参考文献
Nippon Soda Co., Ltd.
Patent: EP2184274 A1, 2010 ;
Location in patent: Page/Page column 6 ;
反应条件
toluene-4-sulfonic acid in dimethyl sulfoxide; benzene
72 h; Heating;
参考文献
Kim, Deog-Il; Schweri, Margaret M.; Deutsch, Howard M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 8 p. 1456 - 1464
