4-甲氧基-2-甲基苄醇合成路线 （共 17 条）
反应条件
potassium permanganate
参考文献
Quelet et al.
Bulletin de la Societe Chimique de France, 1937 , vol. <5> 4, p. 1092,1095
反应条件
Florisil; Celite; pyridinium chlorochromate in dichloromethane 1.3 h; Ambient temperature;
参考文献
Shishido; Yamashita; Hiroya; Fukumoto; Kametani
Tetrahedron, 1989 , vol. 45, # 18 p. 5791 - 5804
反应条件
1: thionyl chloride; DMF / CH2Cl2 / 3 h / 20 °C 2: 23 percent / ethanol / 3.5 h / Heating View Scheme
参考文献
Meyers; Sun; Carlson; Marriner; Katzenellenbogen
Journal of Medicinal Chemistry, 2001 , vol. 44, # 24 p. 4230 - 4251
反应条件
1.1: BuLi; N,N,N'N'-tetramethylethylenediamine / diethyl ether; hexane / 24 h / Heating
1.2: diethyl ether; hexane / 3 h / 20 °C
1.3: aq. H2SO4 / diethyl ether; hexane / 20 h
2.1: 412 mg / pyridine / 4-(dimethylamino)pyridine / CH2Cl2 / 0 - 20 °C
3.1: DPPE-Pd(η3-C3H5)Cp / dimethylsulfoxide / 72 h / 120 °C
View Scheme
参考文献
Kuwano, Ryoichi; Shige, Takenori
Journal of the American Chemical Society, 2007 , vol. 129, # 13 p. 3802 - 3803
参考文献
Shishido KJ.; Yamashita; Hiroya; Fukumoto; Kametani
Tetrahedron Letters, 1989 , vol. 30, # 1 p. 111 - 112
反应条件
sodium tetrahydroborate in ethanol
T=20°C; 2 h;
参考文献
Meyers; Sun; Carlson; Marriner; Katzenellenbogen
Journal of Medicinal Chemistry, 2001 , vol. 44, # 24 p. 4230 - 4251
反应条件
lithium aluminium tetrahydride; Celite in tetrahydrofuran
T=0 - 20°C; 2 h;
参考文献
Shishido; Yamashita; Hiroya; Fukumoto; Kametani
Tetrahedron, 1989 , vol. 45, # 18 p. 5791 - 5804
反应条件
1: With lithium; 4,4'-di-tert-butylbiphenyl in tetrahydrofuran
T=-78°C; 3 h;
2: With water in tetrahydrofuran
T=-78°C; 0.333333 h;
3: With water in tetrahydrofuran
T=-78 - 20°C; Further stages.;
参考文献
Garcia, Daniel; Foubelo, Francisco; Yus, Miguel
Tetrahedron, 2008 , vol. 64, # 19 p. 4275 - 4286
反应条件
1: acetic acid / Electrolysis; Pt anode and cathode
2: LiAlH4 / diethyl ether
View Scheme
参考文献
Ranchella, Michele; Rol, Cesare; Sebastiani, Giovanni V.
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 2 p. 311 - 315
反应条件
lithium aluminium tetrahydride
参考文献
Harding,K.E. et al.
Journal of the American Chemical Society, 1974 , vol. 96, # 8 p. 2540 - 2549
