2-氯-5-三氟甲基吡啶合成路线 （共 80 条）
反应条件
1: With trichlorophosphate in 1,2-dichloro-ethane T=105 - 125°C; 7 h; 2: With triethylamine in 1,2-dichloro-ethane T=-30 - -20°C; 3 h;
参考文献
US2012/259125 A1, ;
Page/Page column 3 ;
反应条件
hydrogen fluoride in (2S)-N-methyl-1-phenylpropan-2-amine hydrate
反应条件
phosphorus pentachloride in water
反应条件
phosphorus pentachloride in water
反应条件
trichlorophosphate in water
反应条件
SbF3 0.166667 h; Heating;
参考文献
Heterocycles, , vol. 22, # 1 p. 117 - 124
反应条件
tert.-butylhydroperoxide; [Cu(I)(CH3CN)4]PF6; sodium hydrogencarbonate in methanol; water T=0 - 20°C; 12 h;
参考文献
Organic Letters, , vol. 14, # 19 p. 4979 - 4981,3
Organic Letters, , vol. 14, # 19 p. 4979 - 4981
反应条件
potassium fluoride; copper(l) iodide; 1,10-phenanthroline in 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide T=20 - 60°C; Inert atmosphere;
参考文献
Chemical Communications, , # 14 p. 1909 - 1911
反应条件
1-methyl-pyrrolidin-2-one; copper(l) iodide T=160°C; 4 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 921 - 926
