2,3,4,6,7,11b-六氢-1H-吡嗪o[2,1-a]异喹啉合成路线 （共 2 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran 6 h; Heating / reflux; 2: With sodium hydroxide; water in tetrahydrofuran T=0°C;
参考文献
MITSUBISHI PHARMA CORPORATION; SANOFI-AVENTIS
Patent: WO2007/119463 A1, 2007 ;
Location in patent: Page/Page column 180 ;
WO 2007/119463 A1
反应条件
1: hydrogenchloride / water / |Inert atmosphere; |Reflux 2: lithium aluminium tetrahydride / tetrahydrofuran / 10 h / 0 °C / |Inert atmosphere; |Reflux View Scheme
参考文献
Wang, Wen-Long; Song, Li-Jun; Chen, Xia; Yin, Xu-Ren; Fan, Wen-Hua; Wang, Gu-Ping; Yu, Chuan-Xin; Feng, Bainian
Molecules, 2013 , vol. 18, # 8 p. 9163 - 9178
