8-氯-2-甲基-4-羟基喹啉合成路线 (共 4 条)
反应条件
in diphenylether T=220°C; 0.116667 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GmbH; BOEHRINGER INGELHEIM PHARMA GmbH and CO KG
Patent: WO2006/85 A1, 2006 ;
Location in patent: Page/Page column 82-83 ;
WO 2006/000085 A1
反应条件
paraffin oil T=240°C;
参考文献
Hughes; Lions
Journal and Proceedings of the Royal Society of New South Wales, 1937 , vol. 71, p. 458,459
反应条件
1: aqueous hydrochloric acid 2: paraffin oil / 240 °C View Scheme
参考文献
Krahler; Burger
Journal of the American Chemical Society, 1942 , vol. 64, p. 2417
参考文献
Krahler; Burger
Journal of the American Chemical Society, 1942 , vol. 64, p. 2417