N-羟基邻苯二甲酰亚胺合成路线 （共 297 条）
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; 19 h;
参考文献
CRYPTOPHARMA PTY LTD; MCALLISTER, David, James; LAMBERT, John, Nicholas
Patent: WO2004/101595 A1, 2004 ;
Location in patent: Page 78-79 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=0 - 50°C; Mitsunobu reaction;
参考文献
Alanine, Alexander; Bourson, Anne; Buettelmann, Bernd; Gill, Ramanjit; Heitz, Marie-Paule; Mutel, Vincent; Pinard, Emmanuel; Trube, Gerhard; Wyler, Rene
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 19 p. 3155 - 3159
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran 24 h; Heating / reflux;
参考文献
CRYPTOPHARMA PTY LTD
Patent: WO2008/124878 A1, 2008 ;
Location in patent: Page/Page column 41-42 ;
反应条件
triethylamine in N,N-dimethyl-formamide T=0 - 5°C; 72 h;
参考文献
Zlotorzynska, Maria; Sammis, Glenn M.
Organic Letters, 2011 , vol. 13, # 23 p. 6264 - 6267
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=0 - 50°C; Mitsunobu reaction;
参考文献
Alanine, Alexander; Bourson, Anne; Buettelmann, Bernd; Gill, Ramanjit; Heitz, Marie-Paule; Mutel, Vincent; Pinard, Emmanuel; Trube, Gerhard; Wyler, Rene
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 19 p. 3155 - 3159
反应条件
triethylamine in N,N-dimethyl-formamide 36 h;
参考文献
Bella, A. Franco; Slawin, Alexandra M. Z.; Walton, John C.
Journal of Organic Chemistry, 2004 , vol. 69, # 18 p. 5926 - 5933
反应条件
1: 2-hydroxy-1,3-isoindolinedione With triethylamine in N,N-dimethyl-formamide 2: triphenyl methyl bromide in N,N-dimethyl-formamide T=20°C;
参考文献
Saczewski, Jaroslaw; Hudson, Alan L.; Rybczynska, Apolonia
Acta Poloniae Pharmaceutica - Drug Research, 2009 , vol. 66, # 6 p. 671 - 680
反应条件
triethylamine in N,N-dimethyl-formamide Heating;
参考文献
Stanciuc, Gabriela; Caproiu, M. Teodor; Caragheorgheopol, Agneta; Caldararu, Horia; Balaban, Alexandru T.; Walter, Robert I.
Journal of Magnetic Resonance (1969-1992), 1987 , vol. 75, # 1 p. 63 - 72
反应条件
1: 2-hydroxy-1,3-isoindolinedione With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 0.166667 h; Inert atmosphere; 2: S-(-)-2-bromopropionic acid in N,N-dimethyl-formamide; mineral oil T=0 - 20°C; Inert atmosphere; 3: With hydrogenchloride in water; N,N-dimethyl-formamide; mineral oil Cooling with ice;
参考文献
Katritzky, Alan R.; Avan, Ilker; Tala, Srinivasa R.
Journal of Organic Chemistry, 2009 , vol. 74, # 22 p. 8690 - 8694
反应条件
isopropylbenzene hydroperoxide in toluene
参考文献
Kuenhle, Adolf; Duda, Mark; Jost, Carsten; Fries, Guido; Kirchhoff, Jochen; Schiffer, Thomas
Patent: US2003/176733 A1, 2003 ;
