9-甲氧基-1,3-二氧杂环戊并[4,5-g]呋喃并[2,3-b]喹啉合成路线 （共 14 条）
反应条件
potassium hydrogensulfate in tetrahydrofuran
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
1: H2, HCl / Pd-C / methanol
2: (i) NBS, (irradiation), CCl4, (ii) collidine
View Scheme
参考文献
Zimmer,H.; Walter,R.
Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, 1963 , vol. 18, p. 669 - 670
反应条件
potassium carbonate in acetone
20 h; Heating;
参考文献
Banerji, J.; Das, A. K.; Ghoshal, N.; Das, B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 594 - 596
反应条件
1: 1.) Na
2: 91 percent / paraffin / 0.17 h / 250 °C
3: 40 percent / dioxane; methanol
4: 31 percent / NaBH4
5: 40 percent / KHSO4 / tetrahydrofuran
View Scheme
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
P2O5; phosphoric acid
36 h; Ambient temperature1) heating on water-bath, 2 h;
参考文献
Ranade, A. C.; Mali, R. S.; Kurnawal, V. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 6 p. 528 - 529
反应条件
1: 40 percent / dioxane; methanol
2: 31 percent / NaBH4
3: 40 percent / KHSO4 / tetrahydrofuran
View Scheme
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
1: 31 percent / NaBH4
2: 40 percent / KHSO4 / tetrahydrofuran
View Scheme
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
1: 91 percent / paraffin / 0.17 h / 250 °C
2: 40 percent / dioxane; methanol
3: 31 percent / NaBH4
4: 40 percent / KHSO4 / tetrahydrofuran
View Scheme
参考文献
Yazima; Munakata
Agricultural and Biological Chemistry, 1980 , vol. 44, # 2 p. 235 - 243
反应条件
1: 61 percent / BBr3 / CH2Cl2 / 0 °C
2: 38 percent / 2) K2CO3 / acetone / 20 h / Heating
View Scheme
参考文献
Banerji, J.; Das, A. K.; Ghoshal, N.; Das, B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 594 - 596
反应条件
1: 1) potassium t-butoxide / 1) ether, t-butylalcohol, 30 min, 0deg C, 2) THF, 6h, reflux
2: 78 percent / 3 percent hydrochloric acid / 5 h / heating on water-bath
3: 43 percent / orthophosphoric acid, phosphorous pentoxide / 36 h / Ambient temperature; 1) heating on water-bath, 2 h
View Scheme
参考文献
Ranade, A. C.; Mali, R. S.; Kurnawal, V. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 6 p. 528 - 529
