N-苄氧羰基-L-天冬氨酸 1,4-二苄酯合成路线 （共 14 条）
反应条件
sodium hydroxide; 15-crown-5 in N,N-dimethyl-formamide T=40°C; 2 h;
参考文献
Mazurov, A. A.; Antonenko, S. V.; Andronati, S. A.
Chemistry of Natural Compounds, 1986 , vol. 22, # 2 p. 208 - 210
Khimiya Prirodnykh Soedinenii, 1986 , vol. 22, # 2 p. 224 - 225
反应条件
sodium carbonate in 1,4-dioxane 18 h; Ambient temperature;
参考文献
Parr, Ian B.; Boehlein, Susan K.; Dribben, Anthony B.; Schuster, Sheldon M.; Richards, Nigel G. J.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 12 p. 2367 - 2378
反应条件
toluene-4-sulfonic acid
参考文献
Davey; Laird; Morley
Journal of the Chemical Society. Perkin transactions 1, 1966 , vol. 5, p. 555 - 566
参考文献
Frankel; Berger
Nature (London, United Kingdom), 1949 , vol. 163, p. 213
Journal of Organic Chemistry, 1951 , vol. 16, p. 1513,1515
反应条件
1: NaHCO3 / methanol; H2O / Heating 2: 2.7 g / K2CO3 / H2O / 4 h / Heating View Scheme
参考文献
Hernandez, J. Nicolas; Martin, Victor S.
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3590 - 3592
参考文献
Berger; Katchalski
Journal of the American Chemical Society, 1951 , vol. 73, p. 4084,4087
反应条件
potassium carbonate in water 4 h; Heating;
参考文献
Hernandez, J. Nicolas; Martin, Victor S.
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3590 - 3592
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene 1.) CH3CN, 160 psig (CO2), 40 deg C, 1 h, 2.) CH3CN, 160 psig (CO2), 85 deg C, 1.5 h; Yield given. Multistep reaction;
参考文献
McGhee, William; Riley, Dennis; Christ, Kevin; Pan, Yi; Parnas, Barry
Journal of Organic Chemistry, 1995 , vol. 60, # 9 p. 2820 - 2830
反应条件
4-methyl-morpholine in water; acetonitrile T=30°C; P=7500600 Torr; 96 h;
参考文献
Yamamoto, Yoshinori; Furuta, Toshiaki; Matsuo, Jiro; Kurata, Tetsuro
Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5737 - 5738
反应条件
hydrogen bromide; acetic acid
参考文献
Karlson,R.H. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 2268 - 2275
