2-甲基-4-乙基-6-羟基嘧啶合成路线 （共 12 条）
反应条件
sodium methylate in methanol 1.5 h; Heating;
参考文献
Sato, Masayuki; Ogasawara, Hiromichi; Komatsu, Sachiko; Kato, Tetsuzo
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3848 - 3856
反应条件
methanol; sodium Ambient temperature;
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: ammonia / xylene / 115 °C 2: ammonia / xylene / 115 °C 3: 56 percent / CHCl3 / 2 h / Heating 4: 86 percent / sodium methoxide / methanol / 1.5 h / Heating View Scheme
参考文献
Sato, Masayuki; Ogasawara, Hiromichi; Komatsu, Sachiko; Kato, Tetsuzo
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3848 - 3856
反应条件
1: ammonia / xylene / 115 °C 2: 56 percent / CHCl3 / 2 h / Heating 3: 86 percent / sodium methoxide / methanol / 1.5 h / Heating View Scheme
参考文献
Sato, Masayuki; Ogasawara, Hiromichi; Komatsu, Sachiko; Kato, Tetsuzo
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3848 - 3856
反应条件
1: 56 percent / CHCl3 / 2 h / Heating 2: 86 percent / sodium methoxide / methanol / 1.5 h / Heating View Scheme
参考文献
Sato, Masayuki; Ogasawara, Hiromichi; Komatsu, Sachiko; Kato, Tetsuzo
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 10 p. 3848 - 3856
反应条件
trichlorophosphate 2 h; Heating;
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 41 percent / POCl3 / 2 h / Heating
2: 84 percent / 1.) Mg; 2.) Ni(dppp)Cl2 / diethyl ether / 6 h / Heating
3: 31 percent / m-chloroperbenzoic acid
4: phosphoryl chloride / dioxane / Heating
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 41 percent / POCl3 / 2 h / Heating
2: 84 percent / 1.) Mg; 2.) Ni(dppp)Cl2 / diethyl ether / 6 h / Heating
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 41 percent / POCl3 / 2 h / Heating
2: 81 percent / Na / 2 h / Heating
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
反应条件
1: 41 percent / POCl3 / 2 h / Heating
2: 84 percent / 1.) Mg; 2.) Ni(dppp)Cl2 / diethyl ether / 6 h / Heating
3: 31 percent / m-chloroperbenzoic acid
View Scheme
参考文献
Sakamoto, Takao; Yoshizawa, Hiroshi; Kaneda, Sohichi; Hama, Yoshiaki; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4533 - 4538
