1-氨基-4-异丙基环己烷合成路线 （共 5 条）
反应条件
potassium carbonate 2 h; Heating;
参考文献
Kolczewski, Sabine; Adam, Geo; Cesura, Andrea M.; Jenck, Francois; Hennig, Michael; Oberhauser, Thomas; Poli, Sonia M.; Roessler, Felix; Roever, Stephan; Wichmann, Juergen; Dautzenberg, Frank M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 2 p. 255 - 264
反应条件
hydrogenchloride in diethyl ether; ethyl acetate
参考文献
PROSIDION LIMITED
Patent: WO2008/142454 A1, 2008 ;
Location in patent: Page/Page column 20 ;
WO 2008/142454 A1
反应条件
hydrogen; 5percent Rh/Al2O3 in isopropyl alcohol
T=80°C; P=75007.5 Torr; 18 h;
参考文献
Kolczewski, Sabine; Adam, Geo; Cesura, Andrea M.; Jenck, Francois; Hennig, Michael; Oberhauser, Thomas; Poli, Sonia M.; Roessler, Felix; Roever, Stephan; Wichmann, Juergen; Dautzenberg, Frank M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 2 p. 255 - 264
反应条件
hydrogen; palladium 10 on activated carbon in tetrahydrofuran
16 h;
参考文献
PROSIDION LIMITED
Patent: WO2008/142454 A1, 2008 ;
Location in patent: Page/Page column 20 ;
WO 2008/142454 A1
参考文献
Johnston; McCaleb; Opliger; Laster; Montgomery
Journal of medicinal chemistry, 1971 , vol. 14, # 17 p. 600 - 614
