(3S,4S,5R)-2-氰基四氢-2H-吡喃-3,4,5-三基三乙酸酯合成路线 (共 9 条)
反应条件
in tetrahydrofuran reduction;
参考文献
Marshall, Philip J.; Sinnott, Michael L.; Smith, Paul J.; Widdows, Danny
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 366 - 376
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
0.666667 h; Heating;
参考文献
Somsak, Laszlo; Batta, Gyula; Farkas, Istvan
Carbohydrate Research, 1983 , vol. 124, p. 43 - 52
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
Heating;
参考文献
Somsak, Laszlo; Batta, Gyula; Farkas, Istvan
Carbohydrate Research, 1982 , vol. 106, p. C4 - C11
反应条件
1: 86 percent / H2S, 4-dimethylaminopyridine / ethanol / 8 h / 55 - 60 °C
2: ethanol / 0.83 h / Heating
3: 58 percent / NH3 / methanol
View Scheme
参考文献
Kovacs; Herczegh; Batta; Farkas
Tetrahedron, 1991 , vol. 47, # 29 p. 5539 - 5548
反应条件
phosphorus trichoride in pyridine
T=20°C;
参考文献
McMillan, Keith G.; Tackett, Miles N.; Dawson, Alice; Fordyce, Euan; Paton, R. Michael
Carbohydrate Research, 2006 , vol. 341, # 1 p. 41 - 48
反应条件
4 A molecular sieve; boron trifluoride diethyl etherate in acetonitrile
T=20°C; 25 h;
参考文献
Kudelska
Carbohydrate research, 2000 , vol. 329, # 3 p. 687 - 691
反应条件
1: 97 percent / pyridine; CHCl3 / 24 h / 0 - 20 °C
2: 89 percent / sodium acetate / acetic acid / 100 °C
View Scheme
参考文献
Pham-Huu, Duy-Phong; Petrusova, Maria; BeMiller, James N.; Petrus, Ladislav
Journal of Carbohydrate Chemistry, 2000 , vol. 19, # 1 p. 93 - 110
反应条件
1: 74 percent / CHCl3 / 48 h / Heating
2: xylene / 36 h / Heating
View Scheme
参考文献
McMillan, Keith G.; Tackett, Miles N.; Dawson, Alice; Fordyce, Euan; Paton, R. Michael
Carbohydrate Research, 2006 , vol. 341, # 1 p. 41 - 48
反应条件
acetic acid
Ambient temperatureother solvent: benzene, AcOH/water; other temperature: reflux; other additive: pyridine, triethylamine; Product distribution;
参考文献
Somsak, Laszlo; Bajza, Istvan; Batta, Gyula
Liebigs Annalen der Chemie, 1990 , # 12 p. 1265 - 1268