对氯苯乙酸甲酯合成路线

参考文献

ARENA PHARMACEUTICALS, INC.
Patent: WO2008/70111 A2, 2008 ;
Location in patent: Page/Page column 17-18 ;
WO 2008/070111 A2

67-56-1甲醇+

140-53-4对氯苯乙腈

52449-43-1对氯苯乙酸甲酯

参考文献

Stein, Joachim; Dost, Johannes; Sitte, Norbert; Gross, Manfred; Klepel, Manfred; Kuehne, Sabine
Zeitschrift fuer Chemie (Stuttgart, Germany), 1989 , vol. 29, # 8 p. 283 - 284

67-56-1甲醇+

1875-88-34-氯苯乙醇

52449-43-1对氯苯乙酸甲酯

参考文献

Yamamoto, Nobuyuki; Obora, Yasushi; Ishii, Yasutaka
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2937 - 2941

1073-67-24-氯苯乙烯

52449-43-1对氯苯乙酸甲酯+

99-91-2对氯苯乙酮

参考文献

Schnapperelle, Ingo; Hummel, Werner; Groeger, Harald
Chemistry - A European Journal, 2012 , vol. 18, # 4 p. 1073 - 1076

67-56-1甲醇+

99-91-2对氯苯乙酮

52449-43-1对氯苯乙酸甲酯

参考文献

Moriarty, Robert M.; Khosrowshahi, Jaffar S.; Prakash, Om
Tetrahedron Letters, 1985 , vol. 26, # 25 p. 2961 - 2964

参考文献

Higgins, Stanley D.; Thomas, Barry C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 235 - 242

参考文献

Giordano, Claudio; Castaldi, Graziano; Casagrande, Francesco; Abis, Luigi
Tetrahedron Letters, 1982 , vol. 23, # 13 p. 1385 - 1386

186581-53-3重氮甲烷+

1878-66-6对氯苯乙酸

52449-43-1对氯苯乙酸甲酯

参考文献

Lambert,J.B. et al.
Journal of the American Chemical Society, 1977 , vol. 99, # 9 p. 3059 - 3067

67031-09-8

52449-43-1对氯苯乙酸甲酯

参考文献

Nawghare, Beena R.; Lokhande, Pradeep D.
Synthetic Communications, 2013 , vol. 43, # 14 p. 1955 - 1963

104-88-14-氯苯甲醛

52449-43-1对氯苯乙酸甲酯

参考文献

Ogura,K. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 2013 - 2022