2,4-二甲基-1H-吡咯-3-羧酸甲酯合成路线 （共 14 条）
反应条件
ethylene glycol; perchloric acid in benzene 0.5 h; Heatingother diols; TsOH;
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
dimercaptoethane; toluene-4-sulfonic acid in benzene 18 h; Heatingother times;
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
toluene-4-sulfonic acid in benzene 0.0833333 h; Heating;
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
triethylamine in acetonitrile 0.5 h;
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
1: 82 percent / dimethylformamide / Heating 2: 41 percent / PPh3; K2CO3 / Pd(OAc)2 / dimethylformamide / 85 °C View Scheme
参考文献
Grigg, Ronald; Savic, Vladimir
Chemical Communications, 2000 , # 10 p. 873 - 874
反应条件
1: 2.8 g / sodium hydride / tetrahydrofuran / 1 h 2: 24 mg / TsOH*H2O / benzene / 0.08 h / Heating View Scheme
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
toluene-4-sulfonic acid in benzene 18 h; Heating;
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
toluene-4-sulfonic acid in benzene 18 h; Heating;
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
sodium tetrahydroborate; di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; silver trifluoromethanesulfonate; 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=25 - 75°C; 21 h; Inert atmosphere; regioselective reaction;
参考文献
Wang, Heng-Yen; Mueller, Daniel S.; Sachwani, Rachna M.; Kapadia, Rachel; Londino, Hannah N.; Anderson, Laura L.
Journal of Organic Chemistry, 2011 , vol. 76, # 9 p. 3203 - 3221
反应条件
2: 44 percent / silicic acid View Scheme
参考文献
Corriu, Robert J.P.; Moreau, Joel J.E.; Vernhet, Claude
Tetrahedron Letters, 1987 , vol. 28, # 26 p. 2963 - 2966
