17-乙氧羰基-3-甲氧基吗喃合成路线 (共 2 条)
反应条件
boron tribromide in dichloromethane T=0°C; 0.333333 h;
参考文献
CONCERT PHARMACEUTICALS INC.; GRAHAM, Philip B.; SILVERMAN, I. Robert
Patent: WO2010/33801 A1, 2010 ;
Location in patent: Page/Page column 29; 31 ;
反应条件
1: (+)-3-Methoxymorphinan With N-ethyl-N,N-diisopropylamine in chloroform
T=20°C; 0.166667 h;
2: chloroformic acid ethyl ester in chloroform
3 h; Heating / reflux;
参考文献
CONCERT PHARMACEUTICALS INC.
Patent: US2008/280936 A1, 2008 ;
Location in patent: Page/Page column 12 ;