1-(4-甲基苯基)-3-二甲氨基-1-丙酮盐酸盐合成路线 （共 5 条）
反应条件
hydrogenchloride in ethanol 36 h; Heating;
参考文献
Hon, Wai Lam; Murray, Gordon J.; Firth, James D.
Organic Letters, 2005 , vol. 7, # 25 p. 5743 - 5746
反应条件
hydrogenchloride; paraformaldehyde in ethanol; acetone
参考文献
Stauffer Chemical Company
Patent: US4250185 A1, 1981 ;
反应条件
hydrogenchloride in ethanol T=60°C; Mannich reaction;
参考文献
Heterocyclic Communications, , vol. 11, # 2 p. 135 - 138
反应条件
1: 1.) 10percent w/v Na2CO3 / 1.) H2O; 2.) Et2O, -10 deg C, 3 h
2: H2O / 20 °C / pH=5.9 (Soerensen's phosphate buffer)
View Scheme
参考文献
Dimmock; Shyam; Smith
Pharmazie, 1984 , vol. 39, # 7 p. 467 - 470
反应条件
1: NaBH4 / methanol; H2O / 6 h
2: 95 percent / benzene / Ambient temperature
View Scheme
参考文献
Avramova; Dryanovska; Ilarionov
Pharmazie, 1983 , vol. 38, # 7 p. 443 - 444
