4-氨基-5,6-二氯-1,3-苯二磺酰胺合成路线 （共 7 条）
反应条件
sodium hydroxide; iodine; potassium iodide T=0 - 4°C;
参考文献
Supuran, Claudiu T; Briganti, Fabrizio; Tilli, Silvia; Chegwidden; Scozzafava, Andrea
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 703 - 714
反应条件
sodium hydroxide; sodium hypochlorite T=25 - 30°C;
参考文献
Supuran, Claudiu T; Briganti, Fabrizio; Tilli, Silvia; Chegwidden; Scozzafava, Andrea
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 703 - 714
反应条件
sodium hydroxide; sodium hypochlorite
T=25 - 30°C; thiocarbamylation;
参考文献
Scozzafava, Andrea; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 10 p. 1117 - 1120
反应条件
hydrogenchloride; dihydrogen peroxide; acetic acid
参考文献
Novello,F.C. et al.
Journal of Organic Chemistry, 1960 , vol. 25, p. 965 - 970
反应条件
1: NH3
2: aq. H2O2, AcOH, aq. HCl
View Scheme
参考文献
Novello,F.C. et al.
Journal of Organic Chemistry, 1960 , vol. 25, p. 965 - 970
反应条件
1: ClSO3H, NaCl / 150 °C
2: NH3
3: aq. H2O2, AcOH, aq. HCl
View Scheme
参考文献
Novello,F.C. et al.
Journal of Organic Chemistry, 1960 , vol. 25, p. 965 - 970
参考文献
Short,J.H.; Biermacher,U.
Journal of the American Chemical Society, 1960 , vol. 82, p. 1135 - 1138
