2-甲基-4-(6-甲基-3-吡啶基)-3-丁炔-2-醇合成路线 （共 5 条）
反应条件
1: sodium hydroxide / toluene / 2 h / |Inert atmosphere; |Reflux 2: sulfuric acid / toluene / 3 h / 80 °C / |Inert atmosphere View Scheme
参考文献
RSC Advances, , vol. 3, # 40 p. 18544 - 18549
反应条件
1: sodium hydroxide / toluene / 2 h / |Inert atmosphere; |Reflux 2: sulfuric acid / toluene / 3 h / 80 °C / |Inert atmosphere 3: bis(acetylacetonato) palladium; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; potassium phosphate / 1-methyl-pyrrolidin-2-one / 16 h / 100 °C / |Inert atmosphere View Scheme
参考文献
Tartaggia, Stefano; Caporale, Andrea; Fontana, Francesco; Stabile, Paolo; Castellin, Andrea; De Lucchi, Ottorino
RSC Advances, 2013 , vol. 3, # 40 p. 18544 - 18549
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); diisopropylamine
T=60°C; 6 h;
参考文献
Kim, Ho-Joong; Lee, Eunji; Kim, Min Gyu; Kim, Min-Cheol; Lee, Myongsoo; Sim, Eunji
Chemistry - A European Journal, 2008 , vol. 14, # 13 p. 3883 - 3888
反应条件
piperidine; palladium diacetate; tris(4-methylphenyl)-phosphine in 1-methyl-pyrrolidin-2-one; toluene
T=40°C; 16 h; Inert atmosphere; Reagent/catalystSolvent;
参考文献
Tartaggia, Stefano; Caporale, Andrea; Fontana, Francesco; Stabile, Paolo; Castellin, Andrea; De Lucchi, Ottorino
RSC Advances, 2013 , vol. 3, # 40 p. 18544 - 18549
反应条件
1: pyridine / dichloromethane / 1.5 h / 0 °C / |Inert atmosphere
2: piperidine; palladium diacetate; tris(4-methylphenyl)-phosphine / toluene; 1-methyl-pyrrolidin-2-one / 16 h / 40 °C / |Inert atmosphere
View Scheme
参考文献
Tartaggia, Stefano; Caporale, Andrea; Fontana, Francesco; Stabile, Paolo; Castellin, Andrea; De Lucchi, Ottorino
RSC Advances, 2013 , vol. 3, # 40 p. 18544 - 18549
