4-甲氧基-2(1H)-吡啶酮合成路线 （共 12 条）
参考文献
Anderson, Regan J.; Hill, Jonathan B.; Morris, Jonathan C.
Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6204 - 6212
反应条件
1: 4-methoxy-3-(phenylsulfonyl)pyridin-2(1H)-one With potassium tert-butylate; tetra-(n-butyl)ammonium iodide in tetrahydrofuran T=0°C; 2: methyl iodide in tetrahydrofuran T=20°C;
参考文献
Conreaux, David; Bossharth, Emmanuel; Monteiro, Nuno; Desbordes, Philippe; Balme, Genevieve
Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7917 - 7920
反应条件
in methanol; water T=20°C; Hydrolysis; 1 h;
参考文献
Sieburth, Scott McN.; Lin, Chao-Hsiung; Rucando, David
Journal of Organic Chemistry, 1999 , vol. 64, # 3 p. 950 - 953
反应条件
1.1: 70 percent / 3 h / 140 °C 2.1: 90 percent / aq. acetic acid / 4 h / Heating 3.1: potassium tert-butoxide; tetrabutylammonium iodide / tetrahydrofuran / 0 °C 3.2: 51 percent / tetrahydrofuran / 20 °C View Scheme
参考文献
Conreaux, David; Bossharth, Emmanuel; Monteiro, Nuno; Desbordes, Philippe; Balme, Genevieve
Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7917 - 7920
反应条件
1: 75 percent / methanol View Scheme
参考文献
Walters, Michael A.; Shay, John J.
Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7575 - 7578
参考文献
Kaneko, Chikara; Shiba, Kazuhiro; Fujii, Harure; Momose, Yu
Journal of the Chemical Society, Chemical Communications, 1980 , # 24 p. 1177 - 1178
反应条件
1: K2CO3 / H2O / 3 h / Ambient temperature 2: pyridine / 24 h / Ambient temperature 3: 98 percent / benzene / 24 h / Irradiation 4: 27 percent / H2O / diisopropyl ether / 2 h / 20 °C / Pseudomonas fluorescens lipase View Scheme
参考文献
Hongo, Hiroshi; Iwasa, Kazuto; Kabuto, Chizuko; Matsuzaki, Hisao; Nakano, Hiroto
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 11 p. 1747 - 1754
反应条件
trichlorophosphate T=95°C; 16 h;
参考文献
Anderson, Regan J.; Hill, Jonathan B.; Morris, Jonathan C.
Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6204 - 6212
反应条件
1: 83.4 percent / diethyl ether / Irradiation 2: acetone / 100 °C View Scheme
参考文献
Kaneko, Chikara; Shiba, Kazuhiro; Fujii, Harure; Momose, Yu
Journal of the Chemical Society, Chemical Communications, 1980 , # 24 p. 1177 - 1178
反应条件
in acetone
8 h; Irradiation;
参考文献
Kaneko; Naito; Momose; et al.
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 519 - 525
