2,6-二羟基-4-甲基苯甲醛合成路线 （共 32 条）
反应条件
acetyl chloride in methanol
T=18°C; 20 h;
参考文献
Banwell, Martin G.; Chand, Satish
Organic Preparations and Procedures International, 2005 , vol. 37, # 3 p. 275 - 279
反应条件
copper(I) oxide; [2,2']bipyridinyl in diethylene glycol dimethyl ether
9 h; Heating;
参考文献
Pulgarin, Cesar; Tabacchi, Raffaele
Helvetica Chimica Acta, 1989 , vol. 72, p. 1061 - 1065
反应条件
boron tribromide in dichloromethane
T=-70 - 20°C;
参考文献
Natsch, Andreas; Gfeller, Hans; Haupt, Tina; Brunner, Gerhard
Chemical Research in Toxicology, 2012 , vol. 25, # 10 p. 2203 - 2215
参考文献
Asahina; Fuzikawa
Chemische Berichte, 1932 , vol. 65, p. 58
反应条件
1: butyl lithium; diethyl ether / anschliessend mit N-Methyl-formanilid und Behandeln des Reaktionsgemisches mit Eis und wss. HCl
2: AlBr3; carbon disulfide
View Scheme
参考文献
Adams; Mathieu
Journal of the American Chemical Society, 1948 , vol. 70, p. 2120
参考文献
Whalley
Journal of the Chemical Society, 1949 , p. 3278
参考文献
Whalley
Journal of the Chemical Society, 1949 , p. 3278
反应条件
potassium hydroxide in water
Reimer-Tiemann reaction; 4 h; Heating;
参考文献
Srivastava, Vandana; Darokar, Mahendra P.; Fatima, Atiya; Kumar; Chowdhury, Chinmay; Saxena, Hari Om; Dwivedi, Gaurav R.; Shrivastava, Kunal; Gupta, Vivek; Chattopadhyay; Luqman, Suaib; Gupta; Negi, Arvind S.; Khanuja, Suman P.S.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 518 - 525
反应条件
1: 70 percent / Zn(CN)2, AlCl3, HCl / diethyl ether / 18 h / Ambient temperature
2: 96 percent / BBr3 / CH2Cl2 / 27 h / Ambient temperature
3: 81 percent / Cu2O, 2,2'-bipyridyle / bis-(2-methoxy-ethyl) ether / 9 h / Heating
View Scheme
参考文献
Pulgarin, Cesar; Tabacchi, Raffaele
Helvetica Chimica Acta, 1989 , vol. 72, p. 1061 - 1065
反应条件
potassium hydroxide
T=100°C;
参考文献
Suominen
Suomen Kemistilehti B, 1939 , vol. 12, p. 26
Full Text Show Details
Schoepf; Heuck; Duntze
Justus Liebigs Annalen der Chemie, 1931 , vol. 491, p. 220,239
