5-乙酰基-6-甲基-2-氧代-1,2-二羟基吡啶-3-甲腈合成路线 （共 22 条）
反应条件
1: 75 percent / dimethylformamide / 22 h / Ambient temperature
2: 100 percent / ammonium acetate / dimethylformamide / 3 h / 120 - 130 °C
3: 90 percent / 50percent aq. H2SO4 / 18 h / 135 - 140 °C
View Scheme
参考文献
Singh, Baldev; Lesher, George Y.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 2085 - 2091
反应条件
1: 49 percent / 50percent H2SO4 / 7.5 h / Heating
2: 78 percent / various solvent(s) / 3 h / Heating
3: 9.6 percent / conc. HCl, 35percent H2O2 / 1 h / 60 °C
View Scheme
参考文献
Yamanaka; Miyake; Suda; Ohhara; Ogawa
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 6 p. 1556 - 1567
