C-(3-氯-苯基)-c-苯基-甲胺盐酸盐合成路线 (共 3 条)
反应条件
ammonium formate in diethyl ether; nitrobenzene
参考文献
Azwell Inc.
Patent: US6172228 B2, 2001 ;
反应条件
sodium tetrahydroborate; titanium tetrachloride in ethylene glycol dimethyl ether
T=20°C; Reduction; 24 h;
参考文献
Sasse; Stark; Ligneau; Elz; Reidemeister; Ganellin; Schwartz; Schunack
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 5 p. 1139 - 1149
反应条件
1: 69 percent / NH2OH*HCl; Na2CO3 / ethanol / 15 h / Heating
2: 45 percent / NaBH4; TiCl4 / 1,2-dimethoxy-ethane / 24 h / 20 °C
View Scheme
参考文献
Sasse; Stark; Ligneau; Elz; Reidemeister; Ganellin; Schwartz; Schunack
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 5 p. 1139 - 1149