3-(氯甲基)-1-甲基哌啶合成路线 （共 5 条）
反应条件
(i) PhNa, benzene, (ii) /BRN= 103726/, (heating); Multistep reaction;
参考文献
Schindler,O. et al.
Helvetica Chimica Acta, 1963 , vol. 46, p. 1097 - 1108
参考文献
Sterling Drug Inc.
Patent: US5068234 A1, 1991 ;
反应条件
hydrogenchloride
anschliessenden Erwaermen mit Thionylchlorid;
参考文献
Feldkamp et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 3831
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Shurawlew et al.
Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 1668,1669; engl. Ausg. S. 1737, 1738
参考文献
Fujii
Yakugaku Zasshi, 1956 , vol. 76, p. 644,647, 648
Chem.Abstr., 1957 , p. 425
反应条件
in ethanol
T=100°C; 17 h;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2004/96810 A1, 2004 ;
Location in patent: Page 171 ;
