(2,5-二甲氧苯基)乙酰氯合成路线 （共 6 条）
反应条件
thionyl chloride in benzene 3 h; Heating;
参考文献
Cannon; Amoo; Long; Bhatnagar; Flynn
Journal of Medicinal Chemistry, 1986 , vol. 29, # 12 p. 2529 - 2534
反应条件
1: 2N aq. KOH / benzene / 4 h / Heating 2: thionyl chloride / benzene / 3 h / Heating View Scheme
参考文献
Kong, Josephine L. Y.; Loach, Paul A.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 737 - 744
反应条件
pyridine 8 h; Heating;
参考文献
Kong, Josephine L. Y.; Loach, Paul A.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 737 - 744
反应条件
sodium tetrahydroborate in tetrahydrofuran
1.) 0 deg C, 30 min, 2.) reflux, 2 h;
参考文献
Gerdes, John M.; Keil, Robert N.; Shulgin, Alexander T.; Mathis, Chester A.
Journal of Fluorine Chemistry, 1996 , vol. 78, # 2 p. 121 - 129
反应条件
1: 77 percent / pyridine / 8 h / Heating
2: 50 percent / boron tribromide / CH2Cl2 / 1)8h -80 deg C 2)3h room temp.
View Scheme
参考文献
Kong, Josephine L. Y.; Loach, Paul A.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 737 - 744
反应条件
1: 2,2-Dimethyl-[1,3]dioxane-4,6-dione; (2,5-dimethoxy phenyl)acetyl chloride With N-ethyl-N,N-diisopropylamine in dichloromethane
T=0 - 20°C; 4 h;
2: ethanol 2 h; Heating;
参考文献
Terai, Takuya; Kikuchi, Kazuya; Iwasawa, Shin-Ya; Kawabe, Takao; Hirata, Yasunobu; Urano, Yasuteru; Nagano, Tetsuo
Journal of the American Chemical Society, 2006 , vol. 128, # 21 p. 6938 - 6946
