5-溴氨基苯甲酸甲酯合成路线

参考文献

GILEAD SCIENCES, INC.; BABAOGLU, Kerim; BOOJAMRA, Constantine, G.; EISENBERG, Eugene, J.; HUI, Hon Chung; MACKMAN, Richard, L.; PARRISH, Jay, P.; SANGI, Michael; SAUNDERS, Oliver, L.; SIEGEL, Dustin; SPERANDIO, David; YANG, Hai
Patent: WO2011/163518 A1, 2011 ;
WO 2011/163518 A1

100-52-7苯甲醛+

52727-57-85-溴氨基苯甲酸甲酯

1131587-77-32-(苄基氨基)-5-溴苯甲酸甲酯

参考文献

Levesque, Patrick; Fournier, Pierre-Andre
Journal of Organic Chemistry, 2010 , vol. 75, # 20 p. 7033 - 7036

52727-57-85-溴氨基苯甲酸甲酯

1196155-68-66-溴喹啉-3-甲醛

参考文献

Cheng, Yuan; Judd, Ted C.; Bartberger, Michael D.; Brown, James; Chen, Kui; Fremeau Jr., Robert T.; Hickman, Dean; Hitchcock, Stephen A.; Jordan, Brad; Li, Vivian; Lopez, Patricia; Louie, Steven W.; Luo, Yi; Michelsen, Klaus; Nixey, Thomas; Powers, Timothy S.; Rattan, Claire; Sickmier, E. Allen; St. Jean Jr., David J.; Wahl, Robert C.; Wen, Paul H.; Wood, Stephen
Journal of Medicinal Chemistry, 2011 , vol. 54, # 16 p. 5836 - 5857

57-13-6尿素+

52727-57-85-溴氨基苯甲酸甲酯

24088-82-26-溴-2H-苯并[e][1,3]噁嗪-2,4(3H)-二酮

参考文献

ALLERGAN, INC.
Patent: WO2009/143058 A1, 2009 ;
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52727-57-85-溴氨基苯甲酸甲酯

90375-25-0

参考文献

Hahn, Witold E.; Osinski, Janusz
Polish Journal of Chemistry, 1984 , vol. 58, # 4/5/6 p. 411 - 424

29632-82-45-溴-1,2-苯异噻唑-3(2H)-酮 1,1-二氧化物+

62473-92-16-溴-1,2-苯异噻唑-3(2H)-酮 1,1-二氧化物

参考文献

Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;

52727-57-85-溴氨基苯甲酸甲酯

3951-89-17-溴-1,2,3,4-四氢苯并[b]氮杂革-5-酮

参考文献

Seto, Masaki; Aramaki, Yoshio; Okawa, Tomohiro; Miyamoto, Naoki; Aikawa, Katsuji; Kanzaki, Naoyuki; Niwa, Shin-Ichi; Iizawa, Yuji; Baba, Masanori; Shiraishi, Mitsuru
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 5 p. 577 - 590

22130-49-0+

52727-57-85-溴氨基苯甲酸甲酯

52727-58-9

参考文献

Kampe,K.-D.
Synthesis, 1976 , p. 469 - 471

52727-57-85-溴氨基苯甲酸甲酯

636581-61-82-氨基-5-溴-3-硝基硼酸甲酯

参考文献

Charifson, Paul S.; Grillot, Anne-Laure; Grossman, Trudy H.; Parsons, Jonathan D.; Badia, Michael; Bellon, Steve; Deininger, David D.; Drumm, Joseph E.; Gross, Christian H.; LeTiran, Arnaud; Liao, Yusheng; Mani, Nagraj; Nicolau, David P.; Perola, Emanuele; Ronkin, Steven; Shannon, Dean; Swenson, Lora L.; Tang, Qing; Tessier, Pamela R.; Tian, Ski-Kai; Trudeau, Martin; Wang, Tiansheng; Wei, Yunyi; Zhang, Hong; Stamos, Dean
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