3-(4-吡啶基甲基)-1H-吲哚合成路线 （共 7 条）
反应条件
1: With hydrogen; acetic acid; platinum(IV) oxide T=20°C; P=1551.49 Torr; 2 h; 2: With sodium carbonate in water; ethyl acetate
参考文献
ABBOTT LABORATORIES
Patent: US2011/152243 A1, 2011 ;
Location in patent: Page/Page column 41-42 ;
反应条件
in acetone; benzene
10 h; Ambient temperature;
参考文献
Bosch, Joan; Mauleon, David; Feliz, Miguel; Granados, Ricardo
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4836 - 4841
反应条件
1: 85 percent / benzene; acetone / 10 h / Ambient temperature
2: 85 percent / H2, 10percent KOH / PtO2 / ethanol / 40 °C / 760 Torr
View Scheme
参考文献
Bosch, Joan; Mauleon, David; Feliz, Miguel; Granados, Ricardo
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4836 - 4841
反应条件
triethylsilane; trifluoroacetic acid in dichloromethane
T=25°C; 16 h;
参考文献
Zhou, Ping; Li, Yanfang; Meagher, Kristin L; Mewshaw, Richard G; Harrison, Boyd L
Tetrahedron Letters, 2001 , vol. 42, # 42 p. 7333 - 7335
反应条件
1: 97 percent / NaOH / methanol / 18 h / 0 - 20 °C
2: 66 percent / Et3SiH; CF3COOH / CH2Cl2 / 16 h / 25 °C
View Scheme
参考文献
Zhou, Ping; Li, Yanfang; Meagher, Kristin L; Mewshaw, Richard G; Harrison, Boyd L
Tetrahedron Letters, 2001 , vol. 42, # 42 p. 7333 - 7335
反应条件
1: 97 percent / NaOH / methanol / 18 h / 0 - 20 °C
2: 66 percent / Et3SiH; CF3COOH / CH2Cl2 / 16 h / 25 °C
View Scheme
参考文献
Zhou, Ping; Li, Yanfang; Meagher, Kristin L; Mewshaw, Richard G; Harrison, Boyd L
Tetrahedron Letters, 2001 , vol. 42, # 42 p. 7333 - 7335
反应条件
methanol; sodium tetrahydroborate; toluene-4-sulfonic acid
1) t-BuOH, reflux, 3 h, 2) benzene, reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Moldvai, Istvan; Gacs-Baitz, Eszter; Szantay, Csaba
Recueil des Travaux Chimiques des Pays-Bas, 1991 , vol. 110, # 11 p. 437 - 440
