反应条件
1: ethyl 3,4-dimethoxybenzoate With sodium hydride in tetrahydrofuran; dimethyl sulfoxide
T=10 - 15°C; Inert atmosphere;
2: 3-(3,4-dimethoxyphenyl)-5-(3-fluorophenyl)isoxazole in tetrahydrofuran; dimethyl sulfoxide
T=10 - 20°C; Inert atmosphere;
参考文献
LUDWIG-MAXIMILIANS-UNIVERSITAeT MUeNCHEN; MAX-PLANCK-GESELLSCHAFT ZUR FOeRDERUNG DER WISSENSCHAFTEN E. V.; GIESE, Armin; BERTSCH, Uwe; KRETZSCHMAR, Hans; HABECK, Mathias; HIRSCHBERGER, Thomas; TAVAN, Paul; GRIESINGER, Christian; LEONOV, Andrei; RYAZANOV, Sergey; WEBER, Petra
Patent: WO2010/372 A2, 2010 ;
Location in patent: Page/Page column 43-44 ;
