(E,E,Z)-9-(1,3-壬二烯基氧基)-8-壬烯酸合成路线 (共 18 条)
反应条件
1: triethylamine / CH2Cl2 / 0.5 h / -23 °C
2: 100 percent / NaCN / dimethylsulfoxide / 5 h / 20 °C
3: KOH / ethanol / 5 h / Heating
View Scheme
参考文献
Corey, E. J.; Wright, Stephen W.
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1670 - 1673
反应条件
1: 96 percent / KOH / H2O; methanol / 4 h / Heating
2: triethylamine / CH2Cl2 / 0.5 h / -23 °C
3: 100 percent / NaCN / dimethylsulfoxide / 5 h / 20 °C
4: KOH / ethanol / 5 h / Heating
View Scheme
参考文献
Corey, E. J.; Wright, Stephen W.
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1670 - 1673
反应条件
1: 100 percent / NaCN / dimethylsulfoxide / 5 h / 20 °C
2: KOH / ethanol / 5 h / Heating
View Scheme
参考文献
Corey, E. J.; Wright, Stephen W.
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1670 - 1673
反应条件
1: 53 percent / lithium diisopropylaminde / tetrahydrofuran; hexamethylphosphoric acid triamide / 1.5 h / -108 °C
2: 70 percent Turnov. / 1M triethylaluminum, tetrakis(triphenylphosphine)palladium(0) / hexane; 1,2-dichloro-ethane / 10.5 h / 20 °C
3: 96 percent / KOH / H2O; methanol / 4 h / Heating
4: triethylamine / CH2Cl2 / 0.5 h / -23 °C
5: 100 percent / NaCN / dimethylsulfoxide / 5 h / 20 °C
6: KOH / ethanol / 5 h / Heating
View Scheme
参考文献
Corey, E. J.; Wright, Stephen W.
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1670 - 1673
反应条件
1: 70 percent Turnov. / 1M triethylaluminum, tetrakis(triphenylphosphine)palladium(0) / hexane; 1,2-dichloro-ethane / 10.5 h / 20 °C
2: 96 percent / KOH / H2O; methanol / 4 h / Heating
3: triethylamine / CH2Cl2 / 0.5 h / -23 °C
4: 100 percent / NaCN / dimethylsulfoxide / 5 h / 20 °C
5: KOH / ethanol / 5 h / Heating
View Scheme
参考文献
Corey, E. J.; Wright, Stephen W.
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1670 - 1673
反应条件
1: 1.) 2-benzenesulfonyl-3-phenyloxaziridine, pyridine / 1.) methylene dichloride, 0 grad C, 15 min, 2.) addition of hexane, 40 grad C, 30 min
2: LiOH / 1,2-dimethoxy-ethane; H2O / 3 h / 23 °C
View Scheme
参考文献
Corey, E. J.; Nagata, Ryu; Wright, Stephen W.
Tetrahedron Letters, 1987 , vol. 28, # 42 p. 4917 - 4920
反应条件
cell-free preparation from Convallaria majalis roots
pH=7.5; 0.0833333 h; aq. buffer;
参考文献
Ogorodnikova, Anna V.; Latypova, Larisa R.; Mukhitova, Fahima K.; Mukhtarova, Lucia S.; Grechkin, Alexander N.
Phytochemistry, 2008 , vol. 69, # 16 p. 2793 - 2798
反应条件
oxygen
pH=7.5; 0.5 h; aq. buffer;
参考文献
Ogorodnikova, Anna V.; Latypova, Larisa R.; Mukhitova, Fahima K.; Mukhtarova, Lucia S.; Grechkin, Alexander N.
Phytochemistry, 2008 , vol. 69, # 16 p. 2793 - 2798