1: 1-iodo-1-(3,4,5-trimethoxyphenyl)ethylene With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene in water; N,N-dimethyl-formamide T=20°C; Sonogashira coupling; 0.0333333 h; 2: 4-methyl-N-(2-trimethylsilanylethynyl-phenyl)-benzenesulfonamide in water; N,N-dimethyl-formamide T=20°C; 12 h;

1: K2CO3 / methanol / 3 h / 20 °C 2: 97 percent / diethyl zinc / toluene / 3 h / Heating View Scheme