1-(1,3-二甲基-1H-吡唑-4-基)乙酮合成路线 （共 8 条）
反应条件
sulfuric acid 5 h; Inert atmosphereReflux;
参考文献
Taydakov, Ilya V.; Krasnoselskiy, Sergey S.
Synthesis (Germany), 2013 , vol. 45, # 15 art. no. SS-2013-Z0195-OP, p. 2188 - 2192
反应条件
hydrogenchloride in methanol Heatingovernight;
参考文献
Menichi; Boutar; Kokel; et al.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 1 p. 275 - 279
反应条件
sodium methylate in methanol T=40°C; 18 h; Yield given. Yields of byproduct given;
参考文献
Nagarajan, Kuppuswamy; Arya, Vishwa Prakash; Shenoy, Sharada J.
Journal of Chemical Research, Miniprint, 1986 , # 5 p. 1401 - 1443
反应条件
1: 86 percent / 1 h / Heating 2: methanol / 4 h / 0 °C View Scheme
参考文献
Boivin, Roch; Carlson, Eric; Endo, Atsushi; Hansen, Hans; Hawkins, Lynn D.; Ishizaka, Sally; Mackey, Matthew; Narayan, Sridhar; Satoh, Takashi; Schiller, Shawn
Patent: US2013/324547 A1, 2013 ;
反应条件
in methanol T=0°C; 4 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Schenone, Pietro; Mosti, Luisa; Menozzi, Giulia
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1355 - 1361
反应条件
1: 5.6 g / aq.KOH / ethanol / 8 h / Heating 2: MeONa / methanol / 18 h / 40 °C View Scheme
参考文献
Nagarajan, Kuppuswamy; Arya, Vishwa Prakash; Shenoy, Sharada J.
Journal of Chemical Research, Miniprint, 1986 , # 5 p. 1401 - 1443
反应条件
1: diethyl ether / 0 - 20 °C 2: hydrogenchloride / ethanol; water / 0.25 h / 20 °C View Scheme
参考文献
Boivin, Roch; Carlson, Eric; Endo, Atsushi; Hansen, Hans; Hawkins, Lynn D.; Ishizaka, Sally; Mackey, Matthew; Narayan, Sridhar; Satoh, Takashi; Schiller, Shawn
Patent: US2013/324547 A1, 2013 ;
反应条件
in diethyl ether 18 h; Ambient temperature;
参考文献
Nagarajan, Kuppuswamy; Arya, Vishwa Prakash; Shenoy, Sharada J.
Journal of Chemical Research, Miniprint, 1986 , # 5 p. 1401 - 1443
