2,3-二甲基-5-亚甲基-2-环戊烯-1-酮合成路线 （共 64 条）
反应条件
1: 100 percent / KHCO3 / ethanol
2: 80 percent / K2CO3 / ethanol
View Scheme
参考文献
Mikolajczyk, M.; Grzejszczak, S.; Midura, W.; Zatorski, A.
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 18, p. 175 - 178
反应条件
sodium hydroxide in dimethyl sulfoxide
1 h; temp.: 0 deg C to room temp.;
参考文献
Takahashi; Kosugi; Uda
Journal of the Chemical Society - Series Chemical Communications, 1982 , vol. No. 9, p. 496 - 497
反应条件
1: LDA, TMEDA / tetrahydrofuran / Ambient temperature
2: 93 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide
3: 400 - 450 °C / 0.05 Torr
View Scheme
参考文献
Siwapinyoyos; Thebtaranonth
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 598 - 599
反应条件
1: 66 percent / 1.) N-chlorosuccinimide, dimethyl sulfide, 2.) triethylamine / toluene / 1.) -25 deg C, 2 h, 2.) -25 deg C, 5 min
2: 75 percent / 2 percent ethanolic sodium hydroxide / ethanol / 2 h / Ambient temperature
3: 80 percent / potassium carbonate / ethanol; H2O / 8 h / Ambient temperature
View Scheme
参考文献
Mikolajczyk, Marian; Zatorski, Andrzej
Journal of Organic Chemistry, 1991 , vol. 56, # 3 p. 1217 - 1223
反应条件
T=400 - 450°C; P=0.05 Torr; Yield given;
参考文献
Siwapinyoyos; Thebtaranonth
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 598 - 599
反应条件
1: 62 percent / 2percent NaOH / ethanol / 96 h / Heating
2: 1.) Br2, 2.) Zn / 1.) CCl4, 23 deg C, 10 h, 2.) Et2O, acetic acid, from 10 to 23 deg C, 40 min
View Scheme
参考文献
Welch; Assercq; Loh; Glase
Journal of Organic Chemistry, 1987 , vol. 52, # 8 p. 1440 - 1450
反应条件
1: 93 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide
2: 400 - 450 °C / 0.05 Torr
View Scheme
参考文献
Siwapinyoyos; Thebtaranonth
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 598 - 599
反应条件
1: 91 percent / LDA / tetrahydrofuran; hexamethylphosphoric acid triamide
2: 400 - 450 °C / 0.05 Torr
View Scheme
参考文献
Siwapinyoyos; Thebtaranonth
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 598 - 599
反应条件
1: LDA, TMEDA / tetrahydrofuran / Ambient temperature
2: 400 - 450 °C / 0.05 Torr
View Scheme
参考文献
Siwapinyoyos; Thebtaranonth
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 598 - 599
反应条件
T=600 - 630°C; P=15 Torr;
参考文献
Koller, Manuel; Karpf, Martin; Dreiding, Andre S.
Helvetica Chimica Acta, 1986 , vol. 69, p. 560 - 579
