acetate de sodium anhydre; iodure de dimethyl-3,4(hydroxyethyl-2)-5 thiazolium-1,3; triethylamine in ethanol 0.75 h; Heating;

tetrabutylammonium hexanitratocerate(IV); potassium carbonate in acetonitrile T=0°C; 2 h;

benzoic acid; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in toluene T=110°C; 24 h; Title compound not separated from byproducts.;

hydrogenchloride T=80°C; 0.666667 h;

1.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C 1.2: 38 percent / tetrahydrofuran / -78 - 20 °C 2.1: 19 percent Spectr. / [Ru(PPh3)3(CO)H2]; Xantphos; benzoic acid / toluene / 24 h / 110 °C View Scheme