N-(2-氟苯基)-3-氧代丁酰胺合成路线 （共 5 条）
参考文献
KALYPSYS, INC.
Patent: US2008/139558 A1, 2008 ;
Location in patent: Page/Page column 34 ;
US 20080139558 A1
反应条件
in acetonitrile
T=160°C; P=7500.75 Torr; 0.5 h; Microwave irradiation;
参考文献
Wlodarczyk, Nicolas; Simenel, Catherine; Delepierre, Muriel; Barale, Jean-Christophe; Janin, Yves L.
Synthesis, 2011 , # 6 art. no. T51110SS, p. 934 - 942
反应条件
in benzene
T=23°C; 18 h;
参考文献
Powers, Larry J.; Fogt, S. W.; Ariyan, Z. S.; Rippin, D. J.; Heilman, R. D.; Matthews, Richard J.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 604 - 609
反应条件
in xylene
T=146.85°C;
参考文献
Chisholm, Greig; Kennedy, Alan R.; Beaton, Laura; Brook, Eve
Acta Crystallographica Section C: Crystal Structure Communications, 2002 , vol. 58, # 11 p. o645-o648
反应条件
sodium acetate in tetrahydrofuran
24 h; Reflux;
参考文献
Li, Suhua; Chen, Gang; Feng, Chen-Guo; Gong, Wei; Yu, Jin-Quan
Journal of the American Chemical Society, 2014 , vol. 136, # 14 p. 5267 - 5270
