4-(溴甲基)-1,3-噻唑合成路线 （共 4 条）
反应条件
N-bromosuccinmide in tetrachloromethane
参考文献
PFIZER JAPAN INC.; HASHIZUME, Yoshinobu; PFIZER INC.
Patent: WO2005/92858 A2, 2005 ;
Location in patent: Page/Page column 129-130 ;
WO 2005/092858 A2
参考文献
CHLORION PHARMA, INC.; UNIVERSITE LAVAL; ATTARDO, Giorgio; TRIPATHY, Sasmita
Patent: WO2010/132999 A1, 2010 ;
Location in patent: Page/Page column 137 ;
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US6384080 B1, 2002 ;
反应条件
in tetrahydrofuran T=20°C; 18 h;
参考文献
Horiuchi, Takao; Takeda, Yasuyuki; Haginoya, Noriyasu; Miyazaki, Masaki; Nagata, Motoko; Kitagawa, Mayumi; Akahane, Kouichi; Uoto, Kouichi
Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 8 p. 991 - 1002
