1-乙基-1,2-二氢-4-羟基-2-氧代-3-喹啉羧酸乙酯合成路线 （共 5 条）
反应条件
potassium carbonate in dimethyl sulfoxide
T=60°C; Alkylation; deacetylation; 15 h;
参考文献
Ukrainets; Taran; Gorokhova; Gorlacheva; Bezuglyi; Turov
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 8 p. 952 - 959
反应条件
sodium acetate; acetic anhydride in acetic acid
Substitution; 100 h; Heating;
参考文献
Ukrainets; Taran; Gorokhova; Gorlacheva; Bezuglyi; Turov
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 8 p. 952 - 959
反应条件
1: Et3N / CH2Cl2 / 8 h / Ambient temperature
2: aq. KOH / 5 h
3: 98 percent / aq. HCl / 1 h
View Scheme
参考文献
Ukrainets, I.V.; Gorokhova, O.V.; Taran, S.G.; Bezuglyi, P.A.; Turov, A.V.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994 , vol. 30, # 7 p. 829 - 836
Khimiya Geterotsiklicheskikh Soedinenii, 1994 , # 7 p. 958 - 966
反应条件
hydrazine hydrate in ethanol
Ambient temperature;
参考文献
Ukrainets, I. V.; Bezuglyi, P. A.; Treskach, V. I.; Kornilov, M. Yu.; Turov, A. V.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 8 p. 912 - 916
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 8 p. 1086 - 1090
反应条件
trichlorophosphate
T=105°C; 10 h;
参考文献
Ukrainets; Bereznyakova; Davidenko; Slobodzian
Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 8 p. 952 - 956
