1: 59 percent / H2 / 10percent Pd/C / ethanol / 2 h / Ambient temperature 2: 5 percent / aq. NaNO2 / aq. H2SO4 / 1.) 0 deg C, 1 h; 2.) room temperature, overnight View Scheme

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '605871', constants.ctx, '0')">cyanoacetic acid ethyl ester</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4122952', constants.ctx, '0')">sodium hydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br />T=20&deg;C;&nbsp;0.5&nbsp;h;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '383713', constants.ctx, '0')">3-nitro-4-chloro-pyridine</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br />T=20&deg;C;&nbsp;2&nbsp;h;&nbsp;<br /> <br /> &nbsp;