反应条件
1: morpholine / isopropyl alcohol / 1 h / 20 - 33 °C 2: triethylamine / methanol / 66.02 h / 25 °C / |Reflux 3: trichlorophosphate / 10 h / 135 °C 4: methanol / 20.25 h / 18 - 25 °C 5: hydrogen; triethylamine; 20 palladium(II) hydroxide on carbon / methanol / 10 h / 25 °C / 2223.8 - 2497.89 Torr 6: sulfuric acid / toluene / 12 h / 70 °C View Scheme
参考文献
Harrington, Peter J.; Johnston, Dave; Moorlag, Henk; Wong, Jim-Wah; Hodges, L. Mark; Harris, Les; McEwen, Gerald K.; Smallwood, Blair
Organic Process Research and Development, 2006 , vol. 10, # 6 p. 1157 - 1166