反应条件
1: 1.) triethylamine, (PPh3)2PdCl2, CuI, 2.) KOH / 1.) room temperature, 2.) methanol, room temperature
2: 1.) BuLi / 1.) THF, -70 deg C, 2.) THF
3: 91 percent / H2, quinoline / Pd(CaCO3), Pb / toluene / Ambient temperature
View Scheme
参考文献
Appelberg, Ulf; Mohell, Nina; Hacksell, Uli
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 4 p. 415 - 420