1: With C38H31Cl2N3O4PRe in 1,4-dioxane T=20°C; 2: With tetrabutyl ammonium fluoride in 1,4-dioxane T=20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Nolin, Kristine A.; Ahn, Richard W.; Kobayashi, Yusuke; Kennedy-Smith, Joshua J.; Toste, F. Dean
Chemistry - A European Journal, 2010 , vol. 16, # 31 p. 9555 - 9562
1: With potassium tert-butylate in tert-butyl alcohol Stobbe-type condensation; 0.75 h; Heating; 2: With hydrogenchloride in acetic acid Hydrolysis; decarboxylation; 3 h; Heating;
参考文献
Wichmann, Juergen; Adam, Geo; Roever, Stephan; Hennig, Michael; Scalone, Michelangelo; Cesura, Andrea M.; Dautzenberg, Frank M.; Jenck, Francois
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 9 p. 839 - 851