1: (+/-)-1-cyano-1,2,3,4-tetrahydronaphthalen-1-yl methoxyacetate With immobilized Pseudomonas cepacia lipase; water in diethyl ether T=30°C; 16 h; Enzymatic reaction; 2: chloro-trimethyl-silane With pyridine in dichloromethane T=20°C; 6 h; optical yield given as percent eeenantioselective reaction;
1: (+/-)-1-cyano-1,2,3,4-tetrahydronaphthalen-1-yl methoxyacetate With immobilized Candida antarctica lipase A; water in diethyl ether T=30°C; 2 h; Enzymatic reaction; 2: chloro-trimethyl-silane With pyridine in dichloromethane T=20°C; 6 h; optical yield given as percent eeenantioselective reaction;
immobilized Candida antarctica lipase A; water in 1,4-dioxane T=40°C; 144 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Rodriguez-Rodriguez, Jesus A.; Gotor, Vicente; Brieva, Rosario
Tetrahedron Asymmetry, 2011 , vol. 22, # 11 p. 1218 - 1224
iron(II) sulfate in tetrahydrofuran; water T=20°C; 16 h; other ozonides; 18O-tracer exp. with ethereal oxygen labeled; reduction also in presence of 18O-labeled H2O or D2O; Product distributionMechanism;
参考文献
Journal of the American Chemical Society, , vol. 121, # 28 p. 6556 - 6562
