反应条件
1: sodium tetrahydroborate / ethanol / 20 - 55 °C / |Inert atmosphere
2: toluene-4-sulfonic acid / toluene / 4 h / 80 - 110 °C / |Inert atmosphere
3: 1,3-dibromo-5,5-dimethyl-hydantoin / toluene; acetone; water / 5 h / 0 - 25 °C / |Inert atmosphere; |Large scale
View Scheme
参考文献
Gala, Dinesh; Dahanukar, Vilas H.; Eckert, Jeffery M.; Lucas, Brian S.; Schumacher, Doris P.; Zavialov, Ilia A.; Buholzer, Patrik; Kubisch, Peter; Mergelsberg, Ingrid; Scherer, Dominik
Organic Process Research and Development, 2004 , vol. 8, # 5 p. 754 - 768