反应条件
1: 2-chloro-acetophenone With alcohol dehydrogenase from Lactobacillus brevis; NADPH; isopropyl alcohol
T=30°C; pH=7.5; 6 h; aq. bufferEnzymatic reaction;
2: sodium cyanide With halohydrin dehalogenase from Mycobacterium sp. GP1
T=30°C; pH=7.5; 18 h; aq. bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Schrittwieser, Joerg H.; Lavandera, Ivan; Seisser, Birgit; Mautner, Barbara; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2293 - 2298
