5-(4-甲氧基苯基)呋喃-2-羧酸甲酯合成路线 （共 3 条）
反应条件
1: With water; sodium hydroxide in tetrahydrofuran; methanol T=23 - 50°C; 2: With hydrogenchloride in tetrahydrofuran; methanol; water T=23°C;
参考文献
Bilodeau, Francois; Brochu, Marie-Christine; Guimond, Nicolas; Thesen, Kris H.; Forgione, Pat
Journal of Organic Chemistry, 2010 , vol. 75, # 5 p. 1550 - 1560
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in methanol; toluene
Suzuki reaction; 6 h; Heating;
参考文献
Lee, Sunkyung; Yi, Kyu Yang; Hwang, Sun Kyung; Lee, Byung Ho; Yoo, Sung-Eun; Lee, Kyunghee
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2882 - 2891
反应条件
PdCl(C3H5)(dppb); potassium acetate in N,N-dimethyl acetamide
T=130°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Fu, Hai Yan; Doucet, Henri
European Journal of Organic Chemistry, 2011 , # 35 p. 7163 - 7173
